Beauty from within is the modern approach to taking care of our skin from the inside out and providing coverage for the entire body. Ceramides are essential lipids that contribute to skin youth and hydration.

Young people’s skin naturally has ceramides that make it look moist, plump, and free of wrinkles. We lose ceramides as we age, resulting in dry and itchy skin, and wrinkles. An oral phytoceramide supplement can help replenish the ceramides in the skin. In addition to restoring the skin’s natural moisture balance, ceramides also helps to diminish the appearance of fine lines and wrinkles, making your skin look radiant and young again.

Oral ceramides are becoming more popular because people feel their skin getting soft and moist again after taking a couple of capsules each day.

Ceramosides™ are a powerful source of highly concentrated phytoceramides and digalactosyl diglycerides (DGDG) from wheat.

Clinical studies have shown that taking a phytoceramide by mouth makes aging and wrinkled skin much more hydrated, smooth, and healthy. An oral ceramide can nourish the dermal layers of aging skin in a way similar to how young skin is kept healthy. Ceramides is the perfect moisturiser for restoring elasticity and a healthy glow to your skin and smoothing out fine lines.

The history of ceramides

Since the early 1990s, major cosmetic companies have been adding ceramides to some skin creams to make up for the loss that comes with getting older. Even though they were advertised as a way to get rid of fine lines, wrinkles, and dry skin, their effects were usually small.

To address this issue, researchers made a ceramides capsule that can be taken by mouth. The capsule delivers ceramides from the bloodstream into the body, where they move up through the skin’s deepest inner layers to dramatically hydrate, smooth, and rejuvenate dry, wrinkled skin. Oral administration of phytoceramides, in contrast to topical applications like face creams, reaches skin cells all over the body.

Working from the inside out

There is evidence that ceramides can reduce the production of melanin, the pigment responsible for age spots and other skin discolorations. This data suggests that wheat-derived phytoceramides taken orally may slow down or even halt the uneven pigmentation of skin aging by replacing ceramides from the inside out. (4-5)

Ceramides are found in the four layers of the epidermis. They are a key part of the natural barrier that keeps in moisture, keeps out infection, and stops wrinkles.

The cells that make up the epidermis of the skin have the appearance of “bricks.” Ceramides are the primary component of the cement that holds these bricks together and are critically important to the skin’s ability to perform its barrier function.

The level of ceramide in the body naturally drops with age and during the colder months. If there are not enough ceramides, then water will be lost through the epidermis, which will lead to dry skin as well as premature aging.

CERAMOSIDES™ works to repair the skin’s water barrier and replenish cracks by delivering new ceramides to the surface of the body through the bloodstream. The skin will become more hydrated and plump.

Clinical Studies

Two separate clinical studies provided conclusive evidence regarding the efficacy of CERAMOSIDES™. A state of the art randomized double blind placebo controlled clinical trial showed outstanding significant results in only 30mg of ceramosides powder.

A visible improvement of the crow’s-feet wrinkles was seen from 8 weeks and was maintained at 12 weeks (7)

A strong skin hydration effect

One clinical trial showed that CERAMOSIDES™ Powder improved skin moisturization by more than 16% vs placebo in only 15 days (23% vs. baseline), and more than 21% vs. placebo after 2 months (36% vs. baseline). Significant results were also observed when measuring the trans-epidermal water loss.

Ceramodes efficacy was also perceived by the subjects: 75% of them felt less pulling sensations and 80% noticed a reduction of scales while 75% of the subjects who took a placebo didn’t feel any improvement.

An exclusive anti-aging action

It is clinically proven that CERAMOSIDES™ Oil and Powder improve skin moisturization by more than 16% vs placebo in only 15 days (23% vs. baseline), and more than 21% vs. placebo after 2 months (36% vs. baseline).

Significant results were also observed when measuring the trans-epidermal water loss.

The double blind clinical trial showed that reduction of wrinkles is significant after 2 weeks and skin elasticity is improved by more than 18% vs. placebo in only 15 days (15% vs. baseline), and more than 26% vs. placebo after 2 months (36% vs. baseline).

The double blind clinical trial showed that reduction of wrinkles is significant after 2 weeks and skin elasticity is improved by more than 18% vs. placebo in only 15 days (15% vs. baseline), and more than 26% vs. placebo after 2 months (36% vs. baseline).

80% of treated subjects felt an improved skin appearance while 65% of the subjects who took a placebo didn’t feel any improvement.

Skin conditions prevention and treatment

Ceramides and other lipids found in the skin form the first line of defense against infection. Researchers have discovered that the risk of numerous skin conditions increases with age due to the breakdown of this barrier. (8)

Summary

Ceramides is a perfectly adapted solution for modern consumers that are looking for new ways to address anti-aging and hydration with demonstrated efficacy and quick action.

Moisturisation is the top need across anti-aging skincare products. Ceramides are well-known to provide moisturising benefits.

CERAMOSIDES™ is gluten free, natural, vegan and contains no GMO, additives or preservatives.

Ceramides is the key ingredient in our Beauty Capsules.

References

1. Guillou S, Ghabri S, Jannot C, et al. The moisturizing effect of a wheat extract food supplement on women’s skin: a randomized, double-blind placebo-controlled trial. Int J Cosmet Sci. 2011;33(2):138-43.

2. Asai S, Miyachi H. . Rinsho Byori. 2007 Mar;55(3):209-15. Japanese. PMID: 17441463.

3. Yilmaz E, Borchert HH. Effect of lipid-containing, positively charged nanoemulsions on skin hydration, elasticity and erythema–an in vivo study. Int J Pharm. 2006;307(2):232-8.

4. Kim DS, Kim SY, Chung JH, et al. Delayed ERK activation by ceramide reduces melanin synthesis in human melanocytes. Cell Signal. 2002;14(9):779-85.

5. Kim DS, Kim SY, Moon SJ, et al. Ceramide inhibits cell proliferation through Akt/PKB inactivation and decreases melanin synthesis in Mel-Ab cells. Pigment Cell Res. 2001;14(2):110-5.

6. Jeong HS, Choi HR, Yun HY, et al. Ceramide PC102 inhibits melanin synthesis via proteasomal degradation of microphthalmia-associated transcription factor and tyrosinase. Mol Cell Biochem. 2013;375(1-2):81-7.

7. Gredeco, Paris, France, 2D.I.V.A. Expertise, Toulouse, France, 3SLB Pharma, Rennes, France, Robertet Group, Grasse, France Polar lipids from wheat extract oil improve skin damages induced by aging: Evidence from a randomized, placebo‐controlled clinical trial in women and an ex vivo study on human skin explant.

8. Proksch E, Brandner JM, Jensen JM. The skin: an indispensable barrier. Exp Dermatol. 2008 Dec;17(12):1063-72. doi: 10.1111/j.1600-0625.2008.00786.x. PMID: 19043850.